Evaluasi efek samping obat pada pasien rawat inap di Rumah Sakit “X” di Jakarta

Authors

  • Iyan Hardiana Sekolah Tinggi Ilmu Kesehatan Buleleng, Indonesia
  • Ivans Panduwiguna Sekolah Tinggi Ilmu Kesehatan Buleleng, Indonesia
  • Aji Abdaul Mujaki Institut Sains dan Teknologi Al-Kamal, Indonesia
  • Jerry Jerry Institut Sains dan Teknologi Al-Kamal, Indonesia
  • Taufani Taufani Institut Sains dan Teknologi Al-Kamal, Indonesia

DOI:

https://doi.org/10.32504/hspj.v6i1.670

Keywords:

Side effects of drug, Naranjo score

Abstract

One of the problems related to the use of drugs is the presence of side effects of drugs. Side Effects Drugs are responses to a drug that is detrimental and undesirable and that occur at doses typically used in humans for the prevention, diagnosis, or therapy of diseases or the modification of physiological functions. Side effects in drug administration are unexpected effects that can arise in treatment. This study aims to determine the number of Side Effects of Drug incidences and what drugs cause Side Effects of the Drug on inpatients at "X" Hospital Jakarta. The research method was descriptive non-experimental research by taking data using retrospective methods. The results of the study showed as many as 139 cases that were suspected of experiencing Adverse Drug Reactions with the number of drug side effects events with a Naranjo score scale of 9-13 must have occurred Adverse Drug Reactions obtained by one patient who experienced Adverse Drug Reactions, then the Naranjo score scale of 4 - 8 most likely Adverse Drug Reactions as many as 86 cases with a percentage of 61.87%, then with a Naranjo score scale 1 - 3 The possibility of Adverse Drug Reactions occurring as many as 52 points with a guarantee of 37.41%.  The class of drugs suspected of causing drug side effects are antibiotics, with as many as 86 cases (61.87%). The drugs suspected of causing drug side effects are ciprofloxacin, as many as ten items (7.19%), and levofloxacin, ten items (7.19%), the form of manifestation of drug side effects was the highest form of Side Effects of the Drug, namely with redness symptoms as many as 33 cases (23.74%). The drugs given to overcome Side Effects of the Drug are dexamethasone 58 drug items (41.73%); these results showed that a high probability of Side Effects of the Drug in patients staying at X Jakarta hospital was still high. It needs to be re-evaluated for its use

References

Peraturan Menteri Kesehatan RI. Peraturan Menteri Kesehatan Republik Indonesia Nomor 72 Tahun 2016 tentang : Standar Pelayanan Kefarmasian di Rumah Sakit. 72 Indonesia; 2016.

Herlambang S. Manajemen Pelayanan Kesehatan Rumah Sakit. Yoyakarta: Gosyen Publishing; 2016.

Badan POM RI. Pedoman Monitoring Efek Samping Obat (MESO) Bagi Tenaga Kesehatan. Jakarta; 2012.

Rahmawati Y, Sunarti S. Permasalahan Pemberian Obat pada Pasien Geriatri di Ruang Perawatan RSUD Saiful Anwar Malang. Jurnal Kedokteran Brawijaya. 2014;28(2):141–5.

Badan Pengawas Obat dan Makanan. Modul Farmakovigilans Bagi Tenaga Profesional Kesehatan. 2020. 1–72 p.

Doherty MJ. Algorithms for assessing the probability of an Adverse Drug Reaction. Respiratory Medicine CME. 2009;2(2):63–7.

Raini M. Antibiotik Golongan Fluorokuinolon: Manfaat dan Kerugian. Media Litbangkes. 2016;26(3):163–74.

Hardiana I, Laksmitawati DR, Ramadaniati HU, Sutarno. Evaluasi Penggunaan Antibiotika Pada Pasien Pneumonia Komunitas di Instalasi Rawat Inap RSPAD Gatot Subroto. Majalah Farmasi dan Farmakologi [Internet]. 2021;25(1):1–6. Available from:

http://journal.unhas.ac.id/index.php/mff

Kristanti P. Efektifitas Dan Efek Samping Penggunaan Obat Antihipertensi Pada Pasien Hipertensi di Puskesmas Kalirungkut Surabaya. Calyptra: Jurnal Ilmiah Mahasiswa Universitas Surabaya. 2015;4(2):1–13.

Sari ID, Yuniar Y, Syaripuddin M. Studi Monitoring Efek Samping Obat Antituberkulosisfdc Kategori 1 di Provinsi Banten Dan Provinsi Jawa Barat. Media Litbangkes. 2014;24(1):28–35.

Seniantara IK, Ivana T, Adang YG. Pengaruh Efek Samping Oat (Obat Anti Tuberculosis) Terhadap Kepatuhan Minum Obat Pada Pasien TBC di Puskesmas. Jurnal keperawatan Suaka Insan. 2018;3(2).

Soleha M, Isnawati A, Fitri N, Adelina R, Soblia HT, Winarsih W. Profil Penggunaan Obat Antiinflamasi Nonstreoid di Indonesia. Jurnal Kefarmasian Indonesia. 2018 Oct 16;109–17.

Aprialdi B, Harfiani E, Yusmaini H. Perbandingan Pemberian Obat Seftriakson dan Levofloksasin Terhadap Kadar Kreatinin Serum Pasien Pneumonia Rawat Inap di RS Citra Sari Husada Karawang Tahun 2017-2018. Seminar Nasional Riset Kedokteran.

Rizka GH, Nansy E, Susanti R, Prof J, Nawawi H. Analisis Efektivitas Seftriakson dan Sefotaksim pada Pasien Rawat Inap Demam Tifoid Anak di RSUD Sultan Syarif Mohamad Alkadrie Kota Pontianak.

Grace LS, Djawad K, Adam AM, Kadir D, Ilmu B, Kulit K, et al. Laporan Kasus Psoriasis Pustular Generalisata yang Diterapi dengan Kortikosteroid Sistemik. Vol. 23, J. Kedokt Meditek. 2017.

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Published

2022-08-22

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