Tinjauan literatur terbaru pada terapi herbal untuk pengobatan Alepocia
DOI:
https://doi.org/10.32504/hspj.v7i2.874Keywords:
Alepocia, herb, hair loss, hair growthAbstract
Baldness or Alopecia is a disease that occurs as a result of excessive and sustainable hair loss. The use of natural ingredients for the treatment of baldness has lower side effects than synthetic drugs. This article provides information about natural ingredients that can be used for the treatment of Alepocia. This article is a review article and written by systematic literature review with the main database was used is Science Direct, PubMed, and Google Scholar. Based on the research results, there are 26 original article and there are 10 plants that consist of candlenut, clove, meniran, cinnamon, pumpkin, shallot, licorice, paku gajah, starfruit, and sansevieria have activity in inhibit the progression of Alepocia and stimulate hair growth with different phytochemical and pharmacological characteristics that provide effectiveness on hair growth both in vitro and in vivo. Candlenut, clove, meniran, cinnamon, pumpkin, shallot, licorice, paku gajah, starfruit, and sansevieria can be used as a nutraceutical for the treatment of Alepocia.
References
Alomaish, A., Gosadi, I., Dallak, F., Durayb, A., Dallak, A., Hakami, J., Hakami, A., Alshamakhy, A., & Mleeh, N. Prevalence of Alepocia and its contributing factors among primary healthcare attendees in the Jazan region, Saudi Arabia. Journal of Family Medicine and Primary Care 2021;10(10):3851.
Fu, D., Huang, J., Li, K., Chen, Y., He, Y., Sun, Y., Guo, Y., Du, L., Qu, Q., Miao, Y., & Hu, Z. Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic Alepocia. Biomedicine and Pharmacotherapy 2021;137.
Legiawati, L., Suseno, L. S., Sitohang, I. B. S., & Pratama, A. I. (2022). Hair disorder in dr. Cipto Mangunkusumo cosmetic dermatology and venereology outpatient clinic of Jakarta, Indonesia: A socio-demographic and clinical evaluation. Dermatology Reports, 14(3).
Park, Y., Choi, K., Kim, H., Lee, J., Park, G., & Kim, J. Sulforaphane, l-menthol, and dexpanthenol as a novel active cosmetic ingredient composition for relieving hair loss symptoms. Cosmetics 2021; 8(3).
Rai, P. B., Khushwaha, P., Jain, N., & Gupta, S. Comparing the therapeutic efficacy of topical minoxidil and finasteride with topical minoxidil and oral finasteride in androgenetic Alepocia: a randomized trial. International Journal of Research in Dermatology 2018;4(3):386.
Fukuda de Castilho, P., Gomes da Silva Dantas, F., Pires de Araújo, R., Almeida Castro, L. H., Souza de Araújo, F. H., Negri, M., Carvalho dos Santos, A., Carvalho Souza, R. I., Lima Cardoso, C. A., Oesterreich, S. A., & Pires de Oliveira, K. M.. General and genetic toxicology studies of Aleurites moluccana (L.) Willd. seeds in vitro and in vivo assays. Journal of Ethnopharmacology 2021;280.
Da, A. M., Leite, S., Fiorese, M. S., Marcela, E., & Bataghin Costa, A. Antioxidants and Growth Factors in the Treatment of Alepocia with Injectables. Ann Surg Edu 2020;1(2):1007.
Shoviantari, F., Liziarmezilia, Z., Bahing, A., Agustina Fakultas Farmasi, L., & Ilmu Kesehatan Bhakti Wiyata, I. Uji Aktivitas Tonik Rambut Nanoemulsi Minyak Kemiri (Aleurites moluccana L.). Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia 2019;6(2):69.
Abadi, H., Winata, H. S., Parhan, Diana, V. E., Chan, A., & Haryani, R. Hair tonic formulation of clove leaves (Syzygium aromaticum) ethanol extract and the effectiveness on rabbit hair growth. International Journal of Applied Pharmaceutics 2020;12(6):245–248.
Carvalho, R. P. R., Lima, G. D. de A., Ribeiro, F. C. D., Ervilha, L. O. G., Oliveira, E. L., Viana, A. G. A., & Machado-Neves, M. Eugenol reduces serum testosterone levels and sperm viability in adult Wistar rats. Reproductive Toxicology 2022;113:110–119.
Nisar, M. F., He, J., Ahmed, A., Yang, Y., Li, M., & Wan, C. Chemical components and biological activities of the genus phyllanthus: A review of the recent literature. In Molecules 2018;23(10).
Patel, S., Sharma, V., Chauhan, N. S., Thakur, M., & Dixit, V. K. Evaluation of hair growth promoting activity of Phyllanthus niruri. In Original Research Article 2015;5(6).
Gupta, R., & Dixit, V. K. Pharmacological investigation of hair growth promotional potential of Phyllanthus niruri Linn. extract against doxorubicin induced Alepocia in experimental rats. International Journal of Pharmacy & Life Sciences 2018;9(11&12): 5977–5984.
Luliana, S., Rawinda, R., Sehro, & Innas, S. Q. Test activity of hair tonic of ethyl acetate fraction from the ethanol extract of meniran (phyllanthus niruri L.) as hair grower to male white rat (rattus norvegicus) wistar strain. Research Journal of Pharmacy and Technology 2019;12(3):999–1002.
Fajar, A., Ammar, G. A., Hamzah, M., Manurung, R., & Abduh, M. Y. Effect of tree age on the yield, productivity, and chemical composition of essential oil from Cinnamomum burmannii. Current Research on Biosciences and Biotechnology 2019;1(1):17–22.
Indriana, L., Pangkahila, W., Aman, G. M., & Journal, I. Topical application of cinnamon (cinnamomum burmanii) essential oil has the same effectiveness as minoxidil in increasing hair length and diameter size of hair follicles in male white Wistar rats (rattus norvegicus). Indonesian Journal of Anti-Aging Medicine 2018;2(1):13–16.
Prommaban, A., Kuanchoom, R., Seepuan, N., & Chaiyana, W. Evaluation of fatty acid compositions, antioxidant, and phar-macological activities of pumpkin (Cucurbita moschata) seed oil from aqueous enzymatic extraction. Plants 2021;10(8).
Hajhashemi, V., Rajabi, P., & Mardani, M. Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model. Avicenna Journal of Phytomedicine 2019;9(6):499–504.
da Cruz, G. K., Martins, M. I. M., Antunes, F. T. T., de Souza, A. H., Wiilland, E. de F., Picada, J. N., & Brum, L. F. da S. Evaluation of the efficacy and toxicity of oral and topical pumpkin oil on the hair growth of mice. Acta Histochemica 2022;124(4).
Teeranachaideekul, V., Parichatikanond, W., Junyaprasert, V. B., & Morakul, B. Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5?-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects. Pharmaceuticals 2022;15(8).
Ruksiriwanich, W., Khantham, C., Muangsanguan, A., Chittasupho, C., Rachtanapun, P., Jantanasakulwong, K., Phimolsiripol, Y., Sommano, S. R., Sringarm, K., Ferrer, E., & Barba, F. J. Phytochemical Constitution, Anti?Inflammation, Anti?Androgen, and Hair Growth?Promoting Potential of Shallot (Allium ascalonicum L.) Extract. Plants 2022;11(11).
Zhao, Q., Zheng, Y., Zhao, D., Zhao, L., Geng, L., Ma, S., Cai, Y., Liu, C., Yan, Y., Izpisua Belmonte, J. C., Wang, S., Zhang, W., Liu, G.-H., & Qu, J. Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration. Protein & Cell 2022.
Utami, S. M., Djajadisastra, J., & Saputri, F. C. Using hair growth activity, physical stability, and safety tests to study hair tonics containing ethanol extract of licorice (Glycyrrhiza glabra Linn.). International Journal of Applied Pharmaceutics 2017;9:44–48.
Upadhyay, S., Upadhyay, P., Ghosh, A. K., & Singh, V. Study of protective effect of Glycyrrhetinic acid in androgen induced Alepocia. Research in Pharmacy 2018;8:10–12.
Murti, B. T. Solvent concentration effect on total flavonoid and total phenolic contents of Averrhoa bilimbi leaf extract. Pharmaciana 2019:9(1):137–144.
Priatna, A. A., Erlin, E., & Romansyah, R. Efektivitas ekstrak daun belimbing wuluh (averrhoa bilimbi l) terhadap pertumbuhan rambut pada hewan uji kelinci lokal (lepus nigricollis). In Jurnal Keguruan dan Ilmu Pendidikan 2022;3(1).
Verma, R., Madaan, A., Joshi, V., Kishore, A., Singh, A. T., Jaggi, M., & Kwan Sung, Y. Dermal Papilla Cells, Keratinocytes, Proliferation, Oxidative stress, VEGF; Dermal Papilla Cells, Keratinocytes, Proliferation, Oxidative stress, VEGF. American Journal of Dermatology and Venereology 2017;6(3):51–57.
Mustarichie, R., Ramdhani, D., & Iskandar, Y. Characteristics and Alepocia activity of Pakis Gajah (Angiopteris evecta (G.Forst) Hoffm.) growing in Galunggung mountainside, West Java. Asian Journal of Pharmaceutical and Clinical Research 2017;10(11):337–340.
Rahmawati, R. P., & Mustarichie, R. Determination of anti-Alepocia compounds from water fraction of the Angiopteris evecta (G. Forst.) Hoffm. L roots. Drug Invention Today 2018;10(9):1869–1875.
Gozali, D., & Mustarichie, R. Hair Tonic Formulation of Anti-Alepocia of Angiopteris evecta Extract. Research Journal of Pharmacy and Technology 2019;12(3):1079–1085.
Dewatisari, W. F., Rumiyanti, L., & Rakhmawati, I. Rendemen dan Skrining Fitokimia pada Ekstrak Daun Sanseviera sp. Jurnal Penelitian Pertanian Terapan 2018;17(3):197.
Kasmawati, H., Mustarichie, R., Halimah, E., Ruslin, R., & A Sida, N. AntiAlepocia Activity and IR-Spectrometry Characterization of Bioactive Compounds From Sansevieria trifasciata P. Egyptian Journal of Chemistry 2022;65(0):19–24.
Mutia, A. C. Hair tonic activity test of the leaves of the law of the law (sansevieria trifasciata prain) on hair growth of male rabbits (lepus nigricollis). Asian Journal of Healthy and Science 2022;1(1):11–21
